Little is known about the roles of integral membrane proteins beyond channels, carriers or receptors in meiotic oocytes. The transmembrane protein Fam70A was previously identified as a likely “female fertility factor” in Fox3a-knockout mouse ovaries where almost all follicles underwent synchronous activation and the mice became infertile very early.

However, whether Fam70A functions in oocyte meiosis remains unknown. Therefore, the present study aimed to address this question.Co-immunoprecipitation, immunogold labelling-electronmicroscopy, co-localization and yeast two-hybrid assays were used to verify the interaction. Antibody or small interfering RNA transfection was used to deplete the proteins.

Immunofluorescence, immunohistochemistry and live tracker staining were used to examine the localization or characterize phenotypes. Western blot was used to examine the protein level. Fam70A was enriched in oocyte membranes important for normal meiosis. Fam70A depletion remarkably disrupted spindle assembly, chromosome congression and first polar body extrusion, which subsequently increased aneuploidy and abnormal fertilization.

Moreover, Fam70A directly bound Wnt5a, the most abundant Wnt member within oocytes. Depletion of either Fam70A or Wnt5a remarkably increased adenomatous polyposis coli (APC), which stabilizes active β-catenin and microtubules. Consequently, depletion of either Fam70A or Wnt5a remarkably increased p-β-catenin (inactive form) and acetylated tubulin, while APC knockdown remarkably decreased these two. Furthermore,

TK216
T13166-50mg	TargetMol Chemicals	50mg	Ask for price
Description: TK216

TK216
T13166-5mg	TargetMol Chemicals	5mg	Ask for price
Description: TK216

TK-129
T60713-10mg	TargetMol Chemicals	10mg	Ask for price
Description: TK-129

TK-129
T60713-1g	TargetMol Chemicals	1g	Ask for price
Description: TK-129

TK-129
T60713-1mg	TargetMol Chemicals	1mg	Ask for price
Description: TK-129

TK-129
T60713-50mg	TargetMol Chemicals	50mg	Ask for price
Description: TK-129

TK-129
T60713-5mg	TargetMol Chemicals	5mg	Ask for price
Description: TK-129

(+)-TK216
T39329-10mg	TargetMol Chemicals	10mg	Ask for price
Description: (+)-TK216

(+)-TK216
T39329-1g	TargetMol Chemicals	1g	Ask for price
Description: (+)-TK216

(+)-TK216
T39329-1mg	TargetMol Chemicals	1mg	Ask for price
Description: (+)-TK216

(+)-TK216
T39329-50mg	TargetMol Chemicals	50mg	Ask for price
Description: (+)-TK216

(+)-TK216
T39329-5mg	TargetMol Chemicals	5mg	Ask for price
Description: (+)-TK216

(-)-TK216
T39330-10mg	TargetMol Chemicals	10mg	Ask for price
Description: (-)-TK216

(-)-TK216
T39330-1g	TargetMol Chemicals	1g	Ask for price
Description: (-)-TK216

(-)-TK216
T39330-1mg	TargetMol Chemicals	1mg	Ask for price
Description: (-)-TK216

(-)-TK216
T39330-50mg	TargetMol Chemicals	50mg	Ask for price
Description: (-)-TK216

(-)-TK216
T39330-5mg	TargetMol Chemicals	5mg	Ask for price
Description: (-)-TK216

Rabbit Anti-SYP monoclonal antibody, clone TK37-96
DMAB5564RH	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-CD86 monoclonal antibody, clone TK31-11
DCABH-9113	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-BDNF monoclonal antibody, clone TK23-10
CABT-L622	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-LDLR monoclonal antibody, clone TK1208
CABT-L624	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-PTEN monoclonal antibody, clone TK20-14
CABT-36410RH	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-STAT1 monoclonal antibody, clone TK12-90
CABT-L620	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-ITGB3 monoclonal antibody, clone TK20-10
CABT-L625	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-SUMO1 monoclonal antibody, clone TK31-14
CABT-L626	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-PIK3CA monoclonal antibody, clone TK1297
DCABH-3236	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-Human MET monoclonal antibody, clone TK20-16
CABT-35309RH	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-Human PDCD1 monoclonal antibody, clone TK12-02
DCABH-3351	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-Calmodulin monoclonal antibody, clone TK27-10
CABT-L623	Creative Diagnostics	100 ul	EUR 932.4

TK05
T13165-10mg	TargetMol Chemicals	10mg	Ask for price
Description: TK05

TK05
T13165-1g	TargetMol Chemicals	1g	Ask for price
Description: TK05

TK05
T13165-1mg	TargetMol Chemicals	1mg	Ask for price
Description: TK05

TK05
T13165-50mg	TargetMol Chemicals	50mg	Ask for price
Description: TK05

TK05
T13165-5mg	TargetMol Chemicals	5mg	Ask for price
Description: TK05

Rabbit Anti-NOTCH1 monoclonal antibody, clone TK316
DCABH-9081	Creative Diagnostics	100 ul	EUR 932.4

Rabbit Anti-Human MSI1 monoclonal antibody, clone TK312
CAB-6711RH	Creative Diagnostics	100 ul	EUR 932.4

Tk1/ Rat Tk1 ELISA Kit
ELI-06771r	Lifescience Market	96 Tests	EUR 1063.2

CD14 mouse monoclonal antibody, clone Tük4, PE
SM1066R	Origene Technologies GmbH	100 Tests	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, PE
SM1066RT	Origene Technologies GmbH	25 Tests	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, FITC
SM1066F	Origene Technologies GmbH	100 µg	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, FITC
SM1066FT	Origene Technologies GmbH	25 µg	Ask for price

CD13 (ANPEP) mouse monoclonal antibody, clone Tük1, PE
AM32324RP-N	Origene Technologies GmbH	500 µl	Ask for price

Lenti ORF particles, Tk1 (GFP-tagged) - Mouse thymidine kinase 1 (Tk1), 200ul, >10^7 TU/mL
MR202813L4V	Origene Technologies GmbH	200 µl	Ask for price

CD13 (ANPEP) mouse monoclonal antibody, clone Tük1, FITC
AM32324FC-N	Origene Technologies GmbH	500 µl	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, Purified
SM1066P	Origene Technologies GmbH	200 µg	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, Purified
SM1066PS	Origene Technologies GmbH	100 µg	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, Purified
SM1066PT	Origene Technologies GmbH	25 µg	Ask for price

Lenti ORF particles, Tk1 (Myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1), 200ul, >10^7 TU/mL
MR202813L3V	Origene Technologies GmbH	200 µl	Ask for price

Lenti ORF particles, Tk1 (GFP-tagged ORF) - Rat thymidine kinase 1, soluble (Tk1), 200ul, >10^7 TU/mL
RR207356L4V	Origene Technologies GmbH	200 µl	Ask for price

CD14 mouse monoclonal antibody, clone Tük4, Low Endotoxin
SM1066LE	Origene Technologies GmbH	500 µg	Ask for price

Lenti ORF particles, TK1 (Myc-DDK tagged) - Human thymidine kinase 1, soluble (TK1), 200ul, >10^7 TU/mL
RC218280L1V	Origene Technologies GmbH	200 µl	Ask for price

Lenti ORF particles, TK1 (mGFP-tagged) - Human thymidine kinase 1, soluble (TK1), 200ul, >10^7 TU/mL
RC218280L2V	Origene Technologies GmbH	200 µl	Ask for price

Lenti ORF particles, TK1 (Myc-DDK tagged) - Human thymidine kinase 1, soluble (TK1), 200ul, >10^7 TU/mL
RC218280L3V	Origene Technologies GmbH	200 µl	Ask for price

Lenti ORF particles, TK1 (mGFP-tagged) - Human thymidine kinase 1, soluble (TK1), 200ul, >10^7 TU/mL
RC218280L4V	Origene Technologies GmbH	200 µl	Ask for price

Lenti ORF particles, Tk1 (Myc-DDK-tagged ORF) - Rat thymidine kinase 1, soluble (Tk1), 200ul, >10^7 TU/mL
RR207356L3V	Origene Technologies GmbH	200 µl	Ask for price

Tk1 (untagged) - Mouse thymidine kinase 1 (Tk1), (10ug)
MC200714	Origene Technologies GmbH	10 µg	Ask for price

Tk1 (untagged ORF) - Rat thymidine kinase 1, soluble (Tk1), (10 ug)
RN207356	Origene Technologies GmbH	10 µg	Ask for price

Tk1 (Myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1)
MR202813	Origene Technologies GmbH	10 µg	Ask for price

TK1 (untagged)-Human thymidine kinase 1, soluble (TK1)
SC118084	Origene Technologies GmbH	10 µg	Ask for price

TK1
pka-036	ProSpec Tany	5µg	EUR 60
Description: Recombinant Human Thymidine Kinase 1

TK2
pka-041	ProSpec Tany	2µg	EUR 60
Description: Recombinant Human Thymidine Kinase 2

TK-6
ABC-TC1237	AcceGen	1 vial	Ask for price
Description: The TK6 cell line has been derived from the WIL-2 cell line. TK6 cells are heterozygous at the thymidine kinase (TK) locus, are resistant to 2-Amino-6-purinethiol (hprt locus) and to ouabain (Na/K ATPase].

TK6
C0003059	Addexbio	One Frozen vial	EUR 450

TK1
CSB-CL023577HU1	Cusabio	10 μg plasmid + 200μl Glycerol	Ask for price

TK1
CSB-CL023577HU2	Cusabio	10 μg plasmid + 200μl Glycerol	Ask for price

TK1 (GFP-tagged) - Human thymidine kinase 1, soluble (TK1)
RG218280	Origene Technologies GmbH	10 µg	Ask for price

TK4b
T61020-10mg	TargetMol Chemicals	10mg	Ask for price
Description: TK4b

TK4b
T61020-1g	TargetMol Chemicals	1g	Ask for price
Description: TK4b

TK4b
T61020-1mg	TargetMol Chemicals	1mg	Ask for price
Description: TK4b

TK4b
T61020-50mg	TargetMol Chemicals	50mg	Ask for price
Description: TK4b

TK4b
T61020-5mg	TargetMol Chemicals	5mg	Ask for price
Description: TK4b

TK4g
T61698-10mg	TargetMol Chemicals	10mg	Ask for price
Description: TK4g

TK4g
T61698-1g	TargetMol Chemicals	1g	Ask for price
Description: TK4g

TK4g
T61698-1mg	TargetMol Chemicals	1mg	Ask for price
Description: TK4g

TK4g
T61698-50mg	TargetMol Chemicals	50mg	Ask for price
Description: TK4g

TK4g
T61698-5mg	TargetMol Chemicals	5mg	Ask for price
Description: TK4g

Tk1 (Myc-DDK-tagged ORF) - Rat thymidine kinase 1, soluble (Tk1), (10 ug)
RR207356	Origene Technologies GmbH	10 µg	Ask for price

TK1 (Myc-DDK-tagged)-Human thymidine kinase 1, soluble (TK1)
RC218280	Origene Technologies GmbH	10 µg	Ask for price

Lenti ORF clone of Tk1 (mGFP-tagged) - Mouse thymidine kinase 1 (Tk1)
MR202813L4	Origene Technologies GmbH	10 µg	Ask for price

TK6(IVGT)
ABL-TC0692	AcceGen	1 vial	Ask for price
Description: TK6(IVGT) Cell Line is from human; Sex: M; Morphology: lymphoblast-like; Profile: Human lymphoblast, thymidine kinase heterozygote. Assay for mutagenesis in heterozygous diploid human lymphoblasts.

Lenti ORF clone of Tk1 (Myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1)
MR202813L3	Origene Technologies GmbH	10 µg	Ask for price

TK1 siRNA
20-abx905590	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

TK1 siRNA
20-abx936847	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

TK1 siRNA
20-abx936848	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

TK2 siRNA
20-abx936849	Abbexa	EUR 661.20 EUR 878.40	15 nmol 30 nmol

Tk2 (GFP-tagged) - Mouse thymidine kinase 2, mitochondrial (Tk2)
MG203589	Origene Technologies GmbH	10 µg	Ask for price

Lenti ORF clone of Tk1 (mGFP-tagged ORF) - Rat thymidine kinase 1, soluble (Tk1), (10 ug)
RR207356L4	Origene Technologies GmbH	10 µg	Ask for price

Tk1 (untagged) - Mouse thymidine kinase 1 (Tk1), transcript variant 2
MC226231	Origene Technologies GmbH	10 µg	Ask for price

Lenti ORF clone of Tk1 (Myc-DDK-tagged ORF) - Rat thymidine kinase 1, soluble (Tk1), (10 ug)
RR207356L3	Origene Technologies GmbH	10 µg	Ask for price

TK1 Rabbit pAb
A5612-100ul	Abclonal	100 ul	EUR 369.6

TK1 Rabbit pAb
A5612-200ul	Abclonal	200 ul	EUR 550.8

TK1 Rabbit pAb
A5612-20ul	Abclonal	20 ul	EUR 219.6

TK1 Rabbit pAb
A5612-50ul	Abclonal	50 ul	EUR 267.6

TK1 Rabbit pAb
E2505612	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

Tk1 (myc-DDK-tagged) - Mouse thymidine kinase 1 (Tk1), transcript variant 2
MR228442	Origene Technologies GmbH	10 µg	Ask for price

TK2 antibody
70R-10316	Fitzgerald	50 ug	EUR 560.4
Description: Affinity purified rabbit polyclonal TK2 antibody

TK1 antibody
70R-20842	Fitzgerald	50 ul	EUR 522
Description: Rabbit polyclonal TK1 antibody

TK1 Antibody
32920-100ul	SAB	100ul	EUR 302.4

TK1 Antibody
ABD7416	Lifescience Market	100 ug	EUR 525.6

TK1 Antibody
1-CSB-PA050267	Cusabio	EUR 266.40 EUR 234.00	100ug 50ug
Description: A polyclonal antibody against TK1. Recognizes TK1 from Human, Monkey. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

TK1 Antibody
1-CSB-PA050268	Cusabio	EUR 266.40 EUR 234.00	100ug 50ug
Description: A polyclonal antibody against TK1. Recognizes TK1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000

TK1 Antibody
1-CSB-PA023577ESR2HU	Cusabio	EUR 266.40 EUR 402.00	100ul 50ul
Description: A polyclonal antibody against TK1. Recognizes TK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

TK1 Antibody
1-CSB-PA023577GA01HU	Cusabio	EUR 716.40 EUR 399.60	150ul 50ul
Description: A polyclonal antibody against TK1. Recognizes TK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF

TK1 Antibody
1-CSB-PA023577HA01HU	Cusabio	EUR 380.40 EUR 402.00	100ug 50ug
Description: A polyclonal antibody against TK1. Recognizes TK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

TK2 antibody
PAab10010	Lifescience Market	100 ug	EUR 463.2

TK2 Antibody
DF15597	Affinity Biosciences	100ul	EUR 280
Description: Human,Mouse

TK2 antibody
CAF50442-100ug	Biomatik Corporation	100ug	EUR 338

TK1 Antibody
CAC07524-100ug	Biomatik Corporation	100ug	EUR 314

TK1 Antibody
CAC07524-50ug	Biomatik Corporation	50ug	EUR 199.2

TK2 antibody
E39-10010	EnoGene	100ug/100ul	EUR 225
Description: Available in various conjugation types.

TK1 antibody
E39-10728	EnoGene	100ug/100ul	EUR 225
Description: Available in various conjugation types.

TK1 Antibody
E308682	EnoGene	200ul	EUR 275
Description: Available in various conjugation types.

TK1 Antibody
E19-7416	EnoGene	100μg/100μl	EUR 225
Description: Available in various conjugation types.

TK1 Antibody
E95612	EnoGene	100μg	EUR 255
Description: Available in various conjugation types.

TK2 Antibody
DF15597-100ul	Affinity Biosciences	100ul	EUR 280

TK2 Antibody
DF15597-200ul	Affinity Biosciences	200ul	EUR 350

TK1 Antibody
32920	SAB	100ul	EUR 439

TK1 protein (His tag)
80R-2349	Fitzgerald	100 ug	EUR 386.4
Description: Purified recombinant Human TK1 Protein (His tag)

TK2 protein (His tag)
80R-2394	Fitzgerald	50 ug	EUR 508.8
Description: Purified recombinant Human TK2 protein (His tag)

Human TK1 ELISA Kit
ELA-E2108h	Lifescience Market	96 Tests	EUR 988.8

Human TK2 ELISA Kit
ELA-E2367h	Lifescience Market	96 Tests	EUR 988.8

TK1 ELISA KIT|Human
EF006187	Lifescience Market	96 Tests	EUR 826.8

TK2 ELISA KIT|Human
EF006284	Lifescience Market	96 Tests	EUR 826.8

pGEX- 2TK Plasmid
PVT0203	Lifescience Market	2 ug	EUR 319.2

TK1 (pS13) Antibody
abx333556-100ul	Abbexa	100 ul	EUR 560.4

TK1 (Ab-13) Antibody
CSB-PA999799-	Cusabio	each	EUR 402
Description: A polyclonal antibody against TK1 (Ab-13). Recognizes TK1 (Ab-13) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

TK1 (Ab-13) Antibody
CSB-PA999799-100ul	Cusabio	100ul	EUR 379.2
Description: A polyclonal antibody against TK1 (Ab-13). Recognizes TK1 (Ab-13) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

anti- TK1 antibody
FNab08718	FN Test	100µg	EUR 658.5
Description: Antibody raised against TK1

anti- TK2 antibody
FNab10010	FN Test	100µg	EUR 658.5
Description: Antibody raised against TK2

Tk1 ORF Vector (Rat) (pORF)
ORF077737	ABM	1.0 ug DNA	EUR 607.2

Tk2 ORF Vector (Rat) (pORF)
ORF077738	ABM	1.0 ug DNA	EUR 607.2

Rat TK1 shRNA Plasmid
20-abx984666	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

TK1 (Center) Rabbit pAb
E2619817	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

TK2 (GFP-tagged) - Human thymidine kinase 2, mitochondrial (TK2), transcript variant 2
RG229735	Origene Technologies GmbH	10 µg	Ask for price

TK2 (untagged)-Human thymidine kinase 2 mitochondrial (TK2) transcript variant 2
SC328373	Origene Technologies GmbH	10 µg	Ask for price

TK1 cloning plasmid
CSB-CL023577HU1-10ug	Cusabio	10ug	EUR 279.6
Description: A cloning plasmid for the TK1 gene.

TK1 cloning plasmid
CSB-CL023577HU2-10ug	Cusabio	10ug	EUR 279.6
Description: A cloning plasmid for the TK1 gene.

TK2 ORF Vector (Human) (pORF)
ORF033943	ABM	1.0 ug DNA	EUR 486

TK1 ORF Vector (Human) (pORF)
ORF010548	ABM	1.0 ug DNA	EUR 114

TK1 ORF Vector (Human) (pORF)
ORF010549	ABM	1.0 ug DNA	EUR 114

Tk1 ORF Vector (Mouse) (pORF)
ORF059629	ABM	1.0 ug DNA	EUR 607.2

Tk2 ORF Vector (Mouse) (pORF)
ORF059630	ABM	1.0 ug DNA	EUR 607.2

Tk1 3'UTR GFP Stable Cell Line
TU271918	ABM	1.0 ml	Ask for price

Tk2 3'UTR GFP Stable Cell Line
TU271919	ABM	1.0 ml	Ask for price

TK1 3'UTR GFP Stable Cell Line
TU075617	ABM	1.0 ml	EUR 1672.8

TK2 3'UTR GFP Stable Cell Line
TU075618	ABM	1.0 ml	EUR 2799.6

Tk1 3'UTR GFP Stable Cell Line
TU170524	ABM	1.0 ml	Ask for price

Tk2 3'UTR GFP Stable Cell Line
TU170525	ABM	1.0 ml	Ask for price

Human TK1 shRNA Plasmid
20-abx954851	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Human TK2 shRNA Plasmid
20-abx954852	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

Mouse TK1 shRNA Plasmid
20-abx973126	Abbexa	EUR 961.20 EUR 1345.20	150 µg 300 µg

TK2 Blocking Peptide
33R-3776	Fitzgerald	100 ug	EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of TK2 antibody, catalog no. 70R-10316

TK1 Blocking Peptide
DF7416-BP	Affbiotech	1mg	EUR 234

TK2 (Myc-DDK-tagged)-Human thymidine kinase 2, mitochondrial (TK2), transcript variant 2
RC229735	Origene Technologies GmbH	10 µg	Ask for price

TK2 (GFP-tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 6
RG231830	Origene Technologies GmbH	10 µg	Ask for price

TK2 (GFP-tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 9
RG231938	Origene Technologies GmbH	10 µg	Ask for price

TK2 (GFP-tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 5
RG232171	Origene Technologies GmbH	10 µg	Ask for price

TK2 (untagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 5
SC331009	Origene Technologies GmbH	10 µg	Ask for price

TK2 (untagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 6
SC331010	Origene Technologies GmbH	10 µg	Ask for price

TK2 (untagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 9
SC331029	Origene Technologies GmbH	10 µg	Ask for price

Tk1 ELISA Kit (Rat) (OKEH04778)
OKEH04778	Aviva Systems Biology	96 Wells	EUR 794.4
Description: Description of target: Catalyzes the transfer of the terminal phosphate of ATP to thymidine to form thymidine 5'-phosphate (dTMP).;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

TK2 (Myc-DDK tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 6
RC231830	Origene Technologies GmbH	10 µg	Ask for price

TK2 (Myc-DDK tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 9
RC231938	Origene Technologies GmbH	10 µg	Ask for price

TK2 (Myc-DDK tagged) - Homo sapiens thymidine kinase 2, mitochondrial (TK2), transcript variant 5
RC232171	Origene Technologies GmbH	10 µg	Ask for price

Human TK1 knockout cell line
ABC-KH15453	AcceGen	1 vial	Ask for price
Description: Human TK1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TK2 knockout cell line
ABC-KH15454	AcceGen	1 vial	Ask for price
Description: Human TK2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

TK1 Conjugated Antibody
C32920	SAB	100ul	EUR 476.4

TK1 Polyclonal Antibody
A70564	EpiGentek	EUR 302.50 EUR 423.50	50 ul 100 ul

TK1 Polyclonal Antibody
A50540	EpiGentek	EUR 684.66 Ask for price Ask for price EUR 423.50	100 µg 20 ul 50 ul 100 ul

TK1 Polyclonal Antibody
A63564	EpiGentek	EUR 684.66 EUR 117.70 EUR 302.50 EUR 423.50	100 µg 20 ul 50 ul 100 ul

TK1 ELISA Kit (Human) (OKAN05209)
OKAN05209	Aviva Systems Biology	96 Wells	EUR 950.4
Description: Description of target: The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.3 pg/mL

TK1 ELISA Kit (Human) (OKCD08262)
OKCD08262	Aviva Systems Biology	96 Wells	EUR 1170
Description: Description of target: The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 29pg/mL

TK1 ELISA Kit (Mouse) (OKCA02465)
OKCA02465	Aviva Systems Biology	96 Wells	EUR 1015.2
Description: Description of target: ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: 1.95 pg/mL

TK2 ELISA Kit (Mouse) (OKEH05168)
OKEH05168	Aviva Systems Biology	96 Wells	EUR 794.4
Description: Description of target: Deoxyribonucleoside kinase that phosphorylates thymidine, deoxycytidine, and deoxyuridine. Also phosphorylates anti-viral and anti-cancer nucleoside analogs. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.78 ng/mL

TK1 ELISA Kit (Mouse) (OKEH05247)
OKEH05247	Aviva Systems Biology	96 Wells	EUR 794.4
Description: Description of target: ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL

TK1 Protein Vector (Rat) (pPM-C-HA)
PV310948	ABM	500 ng	EUR 723.6

TK2 Protein Vector (Rat) (pPM-C-HA)
PV310952	ABM	500 ng	EUR 1399.2

Human TK1 Protein Lysate 20ug
IHUTK1PLLY20UG	Innovative research	each	EUR 211
Description: Human TK1 Protein Lysate 20ug

Human TK2 Protein Lysate 20ug
IHUTK2PLLY20UG	Innovative research	each	EUR 211
Description: Human TK2 Protein Lysate 20ug

Human TK1 knockdown cell line
ABC-KD15453	AcceGen	1 vial	Ask for price
Description: Human TK1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Fam70A depletion remarkably reduced Akt phosphorylation.Fam70A regulates meiosis and quality of mouse oocytes through both canonical and non-canonical Wnt5a signalling pathways.