Purpose: Impaired mucociliary clearance is an initial characteristic of recurrent cough, respiratory infection and chronic respiratory diseases. It has been demonstrated that prolonged inhalation of respirable silica particles results in a variety of pulmonary diseases, but whether the mucociliary system is involved in this process is unclear. This study aims to evaluate the effects of silica particles on mucociliary structure and MUC5B production in respiratory tract.
Materials and Methods: C57BL/6 mice were administered with 2.5 mg silica particles through a single intratracheal instillation. The changes of mucociliary structure and MUC5B expression in trachea was evaluated by HE and AB-PAS staining, transmission electronmicroscopy and immunohistochemistry on days 1, 7, 28 and 84 post-exposure.
Results: The mucociliary structure of airway epithelium was obviously impaired by silica particles, showing disordered, shortened or partially lost cilia on the surface, increased mucus in mucous layer and submucosal glands from day 7 to day 84. A variety of ultrastructural abnormalities were discovered in silica-exposed airway cilia, including absence of central pair microtubules, disorganized microtubules and clusters of axoneme on day 1 and 7.
The numbers of ciliary axonemes and basal bodies in ciliated epithelial cells were significantly decreased, whereas the proportion of abnormal axonemes was gradually increased with exposure to silica particles (P < 0.05). In addition, silica particles significantly decreased MUC5B expression on the surface of airway epithelium on day 28 and 84, but obviously increased its production in submucosal glands from day 1 to day 84 (P < 0.01).
Carboxymethyl Cellulose Sodium Salt (CMC Sodium), Medium Viscosity 250-350CPS |
93797 |
Sisco Laboratories |
500 Gms |
EUR 5.13 |
|
Description: Part A |
PIC 377-250*250-B7541 AC Signs |
223636 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Verzamelplaats bij calamiteit; Description French: Panneau d'évacuation - Point de rassemblement |
PIC 372-250*250-B7541 AC Signs |
223994 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Uitgang die tevens dient als nooduitgang; Description French: Panneau d'évacuation - Sortie |
PIC 352-250*250-B7541 AC Signs |
224141 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Eerste Hulp; Description French: Panneau d'évacuation - Premiers secours |
PIC 374-250*250-B7541 AC Signs |
224143 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Telefoon voor redding en eerste hulp; Description French: Panneau d'évacuation - Téléphone de secours |
PIC 353-250*250-B7541 AC Signs |
224145 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Arts; Description French: Panneau d'évacuation - Médecin |
PIC 354-250*250-B7541 AC Signs |
224147 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Ogen spoelen; Description French: Panneau d'évacuation - Rinçage des yeux |
PIC 355-250*250-B7541 AC Signs |
224149 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Brancard; Description French: Panneau d'évacuation - Civière |
PIC 356-250*250-B7541 AC Signs |
224151 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Veiligheidsdouche; Description French: Panneau d'évacuation - Douche de sécurié |
PIC 350-250*250-B7541 AC Signs |
224153 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Te volgen richting; Description French: Panneau d'évacuation - Flèche directionnelle |
PIC 351-250*250-B7541 AC Signs |
224155 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Pijl; Description French: Panneau d'évacuation - Flèche directionnelle |
PIC 372-250*250-B7541 AC Signs |
224157 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Uitgang die tevens dient als nooduitgang; Description French: Panneau d'évacuation - Sortie |
PIC 382-250*250-B7541 AC Signs |
224160 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Verzamelplaats bij calamiteit; Description French: Panneau d'évacuation - Point de rassemblement |
PIC 376-250*250-B7541 AC Signs |
224166 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Richting nooduitgang; Description French: Panneau d'évacuation - Sortie de secours |
PIC 375-250*250-B7541 AC Signs |
224168 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Vluchtweg links - Vluchtweg rechts; Description French: Panneau d'évacuation - Sortie et issue de secours |
PIC 391-250*250-B7541 AC Signs |
224170 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Vluchtweg links boven; Description French: Panneau d'évacuation - Sortie et issue de secours |
PIC 390-250*250-B7541 AC Signs |
224172 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Vluchtweg links beneden; Description French: Panneau d'évacuation - Sortie et issue de secours |
PIC 391-250*250-B7527 AC Signs |
252324 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Vluchtweg links boven; Description French: Panneau d'évacuation - Sortie et issue de secours |
PIC 350-250*250-B7527 AC Signs |
252401 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Te volgen richting; Description French: Panneau d'évacuation - Flèche directionnelle |
PIC 351-250*250-B7527 AC Signs |
252403 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Pijl; Description French: Panneau d'évacuation - Flèche directionnelle |
PIC 353-250*250-B7527 AC Signs |
252407 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Arts; Description French: Panneau d'évacuation - Médecin |
PIC 354-250*250-B7527 AC Signs |
252409 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Ogen spoelen; Description French: Panneau d'évacuation - Rinçage des yeux |
PIC 356-250*250-B7527 AC Signs |
252413 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Veiligheidsdouche; Description French: Panneau d'évacuation - Douche de sécurié |
PIC 372-250*250-B7527 AC Signs |
252445 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Uitgang die tevens dient als nooduitgang; Description French: Panneau d'évacuation - Sortie |
PIC 374-250*250-B7527 AC Signs |
252459 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Telefoon voor redding en eerste hulp; Description French: Panneau d'évacuation - Téléphone de secours |
PIC 375-250*250-B7527 AC Signs |
252461 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Reddingspictogram - Vluchtweg links - Vluchtweg rechts; Description French: Panneau d'évacuation - Sortie et issue de secours |
BI 372-250*250-B0455 AC Signs |
253507 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse reddingspictogrammen - Uitgang; Description French: Panneau d'évacuation - Sortie |
BI 352-250*250-B0455 AC Signs |
253509 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse reddingspictogrammen - Eerste hulp; Description French: Panneau d'évacuation - Premiers secours |
BI 354-250*250-B0455 AC Signs |
253511 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse reddingspictogrammen - Ogen spoelen; Description French: Panneau d'évacuation - Rinçage des yeux |
BI 356-250*250-B0455 AC Signs |
253513 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse reddingspictogrammen - Veiligheidsdouche; Description French: Panneau d'évacuation - Douche de sécurié |
BI 403-250*250-B0455 AC Signs |
253532 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse brandbestrijdingstekens; Description French: Panneau en drapeau - Extincteur |
V 403-250*250-B0455 AC Signs |
253533 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige brandbestrijdingstekens; Description French: Panneau d'angle - Extincteur |
BI 401-250*250-B0455 AC Signs |
253534 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse brandbestrijdingstekens; Description French: Panneau en drapeau - Lance à incendie |
V 401-250*250-B0455 AC Signs |
253535 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige brandbestrijdingstekens; Description French: Panneau d'angle - Lance à incendie |
BI 412-250*250-B0455 AC Signs |
253536 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse brandbestrijdingstekens; Description French: Panneau en drapeau - Indicateur d’incendie |
V 412-250*250-B0455 AC Signs |
253537 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige brandbestrijdingstekens; Description French: Panneau d'angle - Indicateur d’incendie |
BI 402-250*250-B0455 AC Signs |
253548 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse brandbestrijdingstekens; Description French: Panneau en drapeau - Téléphone de secours |
V 402-250*250-B0455 AC Signs |
253551 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige brandbestrijdingstekens; Description French: Panneau d'angle - Téléphone de secours |
V 372-250*250-B0455 AC Signs |
253607 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige reddingspictogrammen - Uitgang; Description French: Panneau d'évacuation - Sortie |
V 352-250*250-B0455 AC Signs |
253609 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige reddingspictogrammen - Eerste hulp; Description French: Panneau d'évacuation - Premiers secours |
V 354-250*250-B0455 AC Signs |
253611 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige reddingspictogrammen - Ogen spoelen; Description French: Panneau d'évacuation - Rinçage des yeux |
V 356-250*250-B0455 AC Signs |
253613 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige reddingspictogrammen - Veiligheidsdouche; Description French: Panneau d'évacuation - Douche de sécurié |
PIC 241-250*250-B7527 AC Signs |
255346 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 11.64 |
Description: Description Dutch: Informatietekens - Uitgang; Description French: Sortie |
PIC 383-250*250-B7541 AC Signs |
227699 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Richting nooduitgang - rechts; Description French: Panneau d'évacuation - Sortie et issue de secours |
PIC 384-250*250-B7541 AC Signs |
227700 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 5.99 |
Description: Description Dutch: Reddingspictogram - Richting nooduitgang - links; Description French: Panneau d'évacuation - Sortie et issue de secours |
BI 376-250*250-B0455 AC Signs |
227703 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 27.66 |
Description: Description Dutch: Haakse reddingspictogrammen - Nooduitgang; Description French: Panneau d'évacuation - Sortie de secours |
V 376-250*250-B0455 AC Signs |
227707 |
BRADY NV |
Card of 1 Pictogram(s) |
EUR 31.14 |
Description: Description Dutch: Wigvormige reddingspictogrammen - Nooduitgang; Description French: Panneau d'évacuation - Sortie de secours |
BPE, 250 mg |
0414 |
AthenaES |
250 mg |
EUR 348.8 |
|
CTGF (182-250) |
cyt-526 |
ProSpec Tany |
4µg |
EUR 60 |
Description: Recombinant Human Connective Tissue Growth Factor (182-250 a.a.) |
250 uL Syringe |
MLCP-250muSYR-1 |
MiTeGen |
250 uL |
EUR 73 |
Description: 250 uL Syringe |
Trypsin 1:250 |
TB0627 |
Bio Basic |
50g |
EUR 101.76 |
|
JWH 250-d11 |
MBS6018940-5x1mg |
MyBiosource |
5x1mg |
EUR 2565 |
AKAP 250 Antibody |
C10861-100ul |
Assay Biotech |
100μl |
EUR 217 |
Description: AKAP 250 Rabbit Polyclonal Antibody |
AKAP 250 Antibody |
C10861-50ul |
Assay Biotech |
50μl |
EUR 143.5 |
Description: AKAP 250 Rabbit Polyclonal Antibody |
Recombinant Caenorhabditis elegans Putative protein tag-250 (tag-250), partial |
MBS1088119-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Smad2 (Ab-250) Antibody |
8B0998 |
AAT Bioquest |
50ug |
EUR 368 |
Description: Smad2 (Ab-250) Antibody |
MNK1 (Ab-250) Antibody |
8B8144 |
AAT Bioquest |
50ug |
EUR 368 |
Description: MNK1 (Ab-250) Antibody |
AKAP 250 Polyclonal Antibody |
ABP57071-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of AKAP 250 from Human. This AKAP 250 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AKAP 250 at AA range: 270-350 |
AKAP 250 Polyclonal Antibody |
ABP57071-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of AKAP 250 from Human. This AKAP 250 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AKAP 250 at AA range: 270-350 |
AKAP 250 Polyclonal Antibody |
ABP57071-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of AKAP 250 from Human. This AKAP 250 antibody is for IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AKAP 250 at AA range: 270-350 |
Gold Colloid (250 nm) |
62R-GC016 |
Fitzgerald |
20 ml |
EUR 125 |
Description: 250 nm Colloidal Gold particle suspension |
PEG3-tetrazine, 250 mg |
1978-250mg |
Lumiprobe |
250 mg |
EUR 366 |
TGFBR2 (pS225 / 250) Antibody |
abx333097-100ul |
Abbexa |
100 ul |
EUR 560.4 |
|
Smad2 (Ab-250) Antibody |
E11-0998B |
EnoGene |
100μg |
EUR 225 |
Description: Available in various conjugation types. |
AKAP 250 Polyclonal Antibody |
E20-70166 |
EnoGene |
100ug |
EUR 225 |
Description: Available in various conjugation types. |
TGFBR2 antibody (Ser225/250) |
70R-36861 |
Fitzgerald |
100 ug |
EUR 294 |
|
Description: Rabbit Polyclonal TGFBR2 antibody (Ser225/250) |
YELLOW Lysis Kit 250 |
YELLOWE5 |
Next Advance |
250pack |
EUR 657.6 |
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. |
Pink Lysis Kit 250 |
PINKE5 |
Next Advance |
250pack |
EUR 548.4 |
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. |
Green Lysis Kit 250 |
GREENE5 |
Next Advance |
250pack |
EUR 561.6 |
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. |
Navy Lysis Kit 250 |
NAVYE5 |
Next Advance |
250pack |
EUR 656.4 |
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. |
Orange Lysis Kit 250 |
ORANGEE5-RNA |
Next Advance |
250pack |
EUR 644.4 |
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free. |
Red Lysis Kit 250 |
REDE5 |
Next Advance |
250pack |
EUR 624 |
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. |
Brilliant blue G-250 |
T20731-10mg |
TargetMol Chemicals |
10mg |
Ask for price |
|
Description: Brilliant blue G-250 |
Brilliant blue G-250 |
T20731-1g |
TargetMol Chemicals |
1g |
Ask for price |
|
Description: Brilliant blue G-250 |
Brilliant blue G-250 |
T20731-1mg |
TargetMol Chemicals |
1mg |
Ask for price |
|
Description: Brilliant blue G-250 |
Brilliant blue G-250 |
T20731-50mg |
TargetMol Chemicals |
50mg |
Ask for price |
|
Description: Brilliant blue G-250 |
Brilliant blue G-250 |
T20731-5mg |
TargetMol Chemicals |
5mg |
Ask for price |
|
Description: Brilliant blue G-250 |
Anti-AKAP 250 antibody |
STJ91531 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to AKAP 250. |
TGFBR2 (pS225 / 250) Antibody |
abx333097-100g |
Abbexa |
100 µg |
Ask for price |
TGFBR2 (pS225 / 250) Antibody |
abx333097-20g |
Abbexa |
20 µg |
EUR 412.5 |
TGFBR2 (pS225 / 250) Antibody |
abx333097-50g |
Abbexa |
50 µg |
Ask for price |
AKAP 250 Polyclonal Antibody |
E44H03951 |
EnoGene |
100ul |
EUR 255 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
CMKC-250 AB Labels |
049125 |
BRADY NV |
Pack of 3600 Label(s) |
EUR 139.42 |
Description: Description Dutch: Soldeermaskers voor printplaten; Description French: Masque de soudure pour circuits imprimés |
AKAP 250 Polyclonal Antibody |
BT-AP00325-100ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
100ul |
Ask for price |
|
Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP12 (A-kinase anchoring protein 12) encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
AKAP 250 Polyclonal Antibody |
BT-AP00325-20ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
20ul |
Ask for price |
|
Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP12 (A-kinase anchoring protein 12) encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
AKAP 250 Polyclonal Antibody |
BT-AP00325-50ul |
Jiaxing Korain Biotech Ltd (BT Labs) |
50ul |
Ask for price |
|
Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP12 (A-kinase anchoring protein 12) encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Coomassie Blue R 250 |
MBS638938-100g |
MyBiosource |
100g |
EUR 210 |
Coomassie Blue R 250 |
MBS638938-250g |
MyBiosource |
250g |
EUR 335 |
Coomassie Blue R 250 |
MBS638938-50g |
MyBiosource |
50g |
EUR 160 |
Coomassie Blue R 250 |
MBS638938-5x250g |
MyBiosource |
5x250g |
EUR 1365 |
Coomassie Blue G 250 |
MBS638940-100g |
MyBiosource |
100g |
EUR 620 |
Coomassie Blue G 250 |
MBS638940-1kg |
MyBiosource |
1kg |
EUR 1250 |
Coomassie Blue G 250 |
MBS638940-250g |
MyBiosource |
250g |
EUR 915 |
Coomassie Blue G 250 |
MBS638940-25g |
MyBiosource |
25g |
EUR 410 |
Coomassie Blue G 250 |
MBS638940-5x1kg |
MyBiosource |
5x1kg |
EUR 5525 |
Trypsin 1:250 (Porcine) |
MBS653921-100g |
MyBiosource |
100g |
EUR 395 |
Trypsin 1:250 (Porcine) |
MBS653921-1kg |
MyBiosource |
1kg |
EUR 1180 |
Trypsin 1:250 (Porcine) |
MBS653921-25g |
MyBiosource |
25g |
EUR 195 |
Trypsin 1:250 (Porcine) |
MBS653921-500g |
MyBiosource |
500g |
EUR 750 |
Trypsin 1:250 (Porcine) |
MBS653921-5x1kg |
MyBiosource |
5x1kg |
EUR 5200 |
Smad2 (Ab-250) Antibody |
MBS859554-01mg |
MyBiosource |
0.1mg |
EUR 305 |
Smad2 (Ab-250) Antibody |
MBS859554-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
Smad2 (Ab-250) Antibody |
MBS859554-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
Smad2 (Ab-250) Antibody |
MBS859554-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
Smad2 (Ab-250) Antibody |
MBS859554-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
AKAP 250 Polyclonal Antibody |
MBS8521147-01mg |
MyBiosource |
0.1mg |
EUR 305 |
AKAP 250 Polyclonal Antibody |
MBS8521147-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
AKAP 250 Polyclonal Antibody |
MBS8521147-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
AKAP 250 Polyclonal Antibody |
MBS8521147-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
AKAP 250 Polyclonal Antibody |
MBS8521147-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
Brilliant blue G-250 |
MBS5772656-100mg |
MyBiosource |
100mg |
EUR 170 |
Brilliant blue G-250 |
MBS5772656-200mg |
MyBiosource |
200mg |
EUR 200 |
Brilliant blue G-250 |
MBS5772656-500mg |
MyBiosource |
500mg |
EUR 290 |
Brilliant blue G-250 |
MBS5772656-50mg |
MyBiosource |
50mg |
EUR 150 |
Brilliant blue G-250 |
MBS5772656-5mg |
MyBiosource |
5mg |
EUR 145 |
Conclusions: Silica particles could lead to ultrastructural defects in airway cilia, mucus hypersecretion and altered MUC5B expression in trachea, indicating that impaired mucociliary structure and altered MUC5B production might participate in the development of silica-related respiratory diseases.